The human skeleton consists of both fused and individual bones supported and supplemented by ligaments, tendons, muscles and cartilage. It serves as a scaffold which supports organs, anchors muscles, and protects organs such as the brain, lungs and heart. The biggest bone in the body is the femur in the thigh, and the smallest is the stapes bone in the middle ear. In an adult, the skeleton comprises around 30-40% of the total body weight, and half of this weight is water.
Fused bones include those of the pelvis and the cranium. Not all bones are interconnected directly: there are three bones in each middle ear called the ossicles that articulate only with each other. The hyoid bone, which is located in the neck and serves as the point of attachment for the tongue, does not articulate with any other bones in the body, being supported by muscles and ligaments.
Six major Function Of The Skeleton:
- Support - The skeleton provides the framework which supports the body and maintains its shape. The pelvis and associated ligaments and muscles provide a floor for the pelvic structures. Without the ribs, costal cartilages, and the intercostal muscles the lungs would collapse.
- Movement - The joints between bones permit movement, some allowing a wider range of movement than others, e.g. the ball and socket joint allows a greater range of movement than the pivot joint at the neck. Movement is powered by skeletal muscles, which are attached to the skeleton at various sites on bones. Muscles, bones, and joints provide the principal mechanics for movement, all coordinated by the nervous system.
- Protection - The Skeleton protects many vital organs
- Blood Cell Production - The skeleton is the site of haematopoiesis, which takes place in red bone marrow. Marrow is found in the center of long bones.
- Storage - Bone matrix can store calcium and is involved in calcium metabolism, and bone marrow can store iron in ferritin and is involved in iron metabolism. However, bones are not entirely made of calcium,but a mixture of chondroitin sulfate and hydroxyapatite, the latter making up 70% of a bone.
- Endocrine regulation - Bone cells release a hormone called osteocalcin, which contributes to the regulation of blood sugar (glucose) and fat deposition. Osteocalcin increases both the insulin secretion and sensitivity, in addition to boosting the number of insulin-producing cells and reducing stores of fat.
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